FP7 logo euThe SATURN project has received funding from the European Community's Seventh Framework Programme [FP7/2007-2013] under grant agreement n°241796

Impact of Specific Antibiotic Therapies on the Prevalence of Human Host Resistant Bacteria

Partners: Institut D’Investigacions Biomediques August Pi i Sunyer – (IDIBAPS)

The organisation

IDIBAPSIDIBAPS is a research consortium combining the scientific staff from its constituent institutions: Hospital Clínic de Barcelona, the University of Barcelona School of Medicine, the CSIC’s Barcelona Biomedical Research Institute and the staff recruited by the Fundació Clínic. The current number of researchers working in IDIBAPS is approximately 350, and they all have complementary basic and clinical profiles. In addition, there is a sizeable team of qualified graduates in different fields and trainees dedicated to research tasks that support the lines of study of the IDIBAPS scientists.

The fundamental mission of IDIBAPS is to combine clinical research of proven quality with high-level basic research for the prevention and treatment of the most common health problems.

The biomedicine promoted by our professionals, together with their research teams, is aimed at minimising the barriers between laboratories and the treatment of patients. IDIBAPS aims to ensure that medical challenges are smoothly translated into basic research, and that the results obtained in laboratories can be effectively used to benefit patients. Improving people’s health is its ultimate mission.All IDIBAPS research is strictly regulated by the applicable national and international bioethics guidelines. IDIBAPS has an accredited Clinical Research Ethics Committee (CREC) and Animal Experiments Ethical Committee. In addition, the Hospital Clínic Evaluation, Support and Prevention Unit offers advisory and research support services to its researchers and to other public and private institutions.

Key staff involved in the project

Jordi VilaJordi Vila, Professor is the team leader. He is a professor of Microbiology in the School of Medicine, University of Barcelona and Head of the Department of Clinical Bacteriology in the Hospital Clinic. His main research interest is the investigation of the molecular bases of multiresistance mainly in Gram-negative bacteria such as A. baumannii, Stenotrophomonas maltophilia and P. aeruginosa. In addition, his group has investigated in depth the mechanisms of resistance to FQ in different microorganisms, as well as the relationship between quinolone resistance and virulence in uropathogenic E. coli strains. Moreover, his group has contributed to understand the pathogenesis of enteroaggregative E. coli and the mechanisms of resistance to different enteropathogens causing traveller’s diarrhoea. All this research work has taken the form of more than 160 publications in peer-reviewed-scientific journals as well as 20 chapters in books. He is currently the Scientific Officer of ESCMID. The research group is constituted of 1 post-doctoral fellow, 4 PhD students and 1 technician who are specifically working on Acinetobacter and virulence of E. coli.

Ignaci RocaIgnaci Roca is a postdoctoral fellow with a large experience in genetic analysis such as cloning and expression of genes, and generating knock-out of genes. He will perform all work concerning the investigation of the virulence factors and biofilm formation in ESBL-producing Enterobacteriaceae.

Paula Andrea EspinalPaula Andrea Espinal is also a PhD student working on the investigation of the mechanisms of resistance to carbapenems in A. baumannii clinical isolates.

Further information

www.idibaps.org

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