FP7 logo euThe SATURN project has received funding from the European Community's Seventh Framework Programme [FP7/2007-2013] under grant agreement n°241796

Impact of Specific Antibiotic Therapies on the Prevalence of Human Host Resistant Bacteria

Partners: University Medical Centre Utrecht – (UMCU)

Presentation of the organisation

UMCUThe UMC Utrecht is an internationally renowned research and teaching hospital with 1’200 beds and all medical specialties represented. Infection & Immunity is one of five research topics. The UMCU hosts the Department of medical microbiology and the “Julius Center for Health Care Epidemiology and Primary Care”, where researchers from different medical specialties collaborate. Central research themes include, amongst others, antibiotic resistance, epidemiology of infectious diseases and ICU-acquired infections.

AMR has been a central research theme of the department of Medical Microbiology since 1976 and since then numerous scientific publications addressing all aspects of this issue have been produced. Notably, the Dutch “search and destroy” policy, nowadays famous for controlling MRSA in Dutch hospitals, was developed within this department in the early 1980s. The department includes over 100 researchers, most of them involved in molecular/biological laboratory studies.

The Julius Center for Health Care Epidemiology and Primary Care hosts >200 researchers, all involved in epidemiological studies around six central research themes. One of these central themes is Infectious Diseases (headed by Prof. Bonten). Central themes within this research group are AMR (intramural and extramural), respiratory tract infections, hospital-acquired infections and mathematical modelling. The Julius Center harbours extensive experience with large-scale multi-centre intervention trials and epidemiological analyses of large patient databases. The investigators are already co-ordinating or participating in several international EC-funded projects (MOSAR, ACE, CONCORD).

Key staff involved in the project

Marc BontenMarc Bonten, MD, PhD, is professor of molecular epidemiology of infectious diseases, head of the department of Medical Microbiology and head of Infectious Disease research within the Julius Center for Health Sciences and Primary Care. As a researcher he has extensive experience in intervention trials in ICUs, mainly on topics related to (prevention of) ventilator-associated pneumonia and antibiotic resistance. Other research areas include epidemiology of antibiotic resistance and mathematical modelling. On these issues, he has published >170 papers in peer-reviewed scientific journals.

Further information


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